Chapter 9: Cell Growth and Division
Developed by Nancy Manikas (6-20-97)

I. Cell Growth

- growth of an organism is usually due to an increased number of cells.

A. Limits of Cell Growth

1. Surface Area



2. One copy of DNA


-when the cell's efficiency has decreased due to size, it undergoes cell division where the cell divides into two daughter cells.

B. Rates of Cell Growth



C. Controls on Cell Growth

- different rates of cell growth depend on:

- some cells will grow as long as there is _________ and __________. When cells touch, they stop multiplying.

-when conditions change, it can change the growth rate of cells

examples:

D. Uncontrolled Cell Growth

- can occur in a multicellular organism, called ______________. Cells keep growing until they run out of nutrients.

Review converting numbers to scientific notation and back to decimal.

1. 9034000 = _______________ 2. 0.000765 = ______________

3. 0.00000352 = ____________ 4. 40000 = ________________

5. 4.5 x 104 = ______________ 6. 6.2 x 10-3 = _____________

7. -2.4x103 = ______________ 8. 5.5x10-2 = ______________

II. Cell Division = Mitosis and Cytokinesis

A. Chromosomes -structures in a cell which contain the __________ information which is passed from one generation of cells to the next.

For more information, click here.

- the word chromosome means "___________ ___________" because when you dye a cell during cell division, you can see them (but usually not at other times).

-in prokaryotes, DNA is in the form of _________________ molecules.

-in eukaryotes, DNA is in _________ ___________. Cells of each organism contain specific numbers of chromosomes. Humans have ____ chromosomes.

1. Composition of Chromatin

-chromatin makes up _________________.

-between cell divisions, chromatin has the following structure:

-when cell division starts, all the chromatin ______________ (and therefore becomes visible with dye)

-What makes up chromatin? ____________ and _____________

-in 1973, Don Olins, Ada Olins, and Christopher Woodcock fournd that the chromosome's DNA was coiled around special proteins called ____________. These complexes were called ______________.

2. Chromosome Structure

- after replication (before cell division) the chromosome is composed of two _____________ (identical parts) attached at the _____________.

B. The Cell Cycle

-goes from the beginning of one ___________ to the beginning of the next ____________.

-includes ____________, prepares for ____________, divides into two cells and cycle starts over.

-the cell cycle includes:

1. _____________ (a period of active division called the M phase); during this phase, the nucleus divides into _______ nuclei.

2. _____________ (a period of nondivision) which is divided into three parts (see below).

C. Interphase is divided into three parts:

G1 (gap 1) -

S (DNA synthesis) -

G2 (gap 2) -


D. Mitosis is divided into four phases: (remember P-M-A-T!!)

1. Prophase: first phase in mitosis, ___________ phase in mitosis.

-chromosomes appear because they are _____________. You can see ____________ held together by the ______________.

-the _____________ (two tiny structures in the cytoplasm near the nucleus) ____________ and stop on opposite sides of the __________.

-centrioles contain a microtubule protein called ___________.

-chromosomes attach to fibers in the ___________ near the chromatid's centromere. The spindle develops from the _______________.

-chromosomes coil even tighter, the nucleolus ____________, and the nuclear envelope _________________.

Plant Animal

 

2. Metaphase: second phase in mitosis, _____________ phase.

- chromosomes ____________ across the center of the cell (the "equator").

-microtubules connect the _____________ of each chromosome to poles of the _____________.

Plant Animal

 

3. Anaphase: third phase of mitosis

-______________ joining sister chromatids _________, separating the chromatids.

-chromosomes are pulled to the _________ of the cell.

-anaphase ends when the chromosomes ___________ moving.

Plant Animal

4. Telophase: fourth phase of mitosis

- chromosomes begin to ____________

Plant Animal

A review of the stages of mitosis

 

Click here f'or more pictures of mitosis.

E. Cytokinesis

-in animal cells, the ________ _____________ pinches inward like a belt tightening. You end up with _______ cells, each with its own nucleus and cytoplasmic organelles.

- in plant cells, a _________ ____________ forms down the middle of the cell, becomes the cell membrane and eventually the ________ _______ forms.